As shown in Figure 5A, a dramatic decrease in the proliferation of tumor cells measured by Ki67 staining and increased infiltration of human CD3+ T cells were observed in the combination treatment group, and CD3+ T cells that accumulated in the tumor lesions were significantly more than those in the GPC3-28Z CAR-T cell group (Figures 5B,C). The gene discussed is GPC3; the disease is neoplasm.