Among them, microRNAs hsa-miR-26b-5p (miR-26b-5p), hsa-miR-4530 (miR-4530), and hsa-miR-28-5p (miR-28-5p) have been shown to exert crucial influence on tumor growth and migration by modulating AKT (8), ERK (9), and IGF-1 (10) signaling pathways. The gene discussed is IGF1; the disease is neoplasm.