METTL3 can regulate tumor cell progression by modulating the expression of oncogenes such as CUB domain-containing protein 1 (CDCP1) (30), integrin subunit alpha 6 (ITGA6) (66), and mammalian HBXIP (42) or tumor suppressors [such as P53 (67)] in an m6A-dependent manner. This evidence concerns the gene METTL3 and neoplasm.