ABCB1 and ovarian carcinoma: As demonstrated in Figures 6A,B, the co-treatment group of erastin and docetaxel dramatically induced more accumulation in the sub-G1 and G2/M phase in comparison with erastin or docetaxel alone treatment only in A2780/Taxol cell but not in A2780 cells, suggesting that erastin can enhance the docetaxel-induced cell cycle arrest in the ABCB1-overexpressing ovarian cancer cells.