To find out whether erastin enhances the sensitivity of docetaxel in the ABCB1-overexpressing ovarian cancer cells is due to downregulation of the expression of ABCB1 or the inhibition of ABCB1 activity, we valued the protein expression of ABCB1 as well as the intracellular aggregation level of rhodamine 123 (ABCB1 substrate) in the pre-incubation of erastin or absence of erastin. Here, ABCB1 is linked to ovarian carcinoma.