MTOR and neoplasm: On the other hand, it was demonstrated that under radiation stress, mTOR relocates to mitochondria in MCF7, HCT116, and U87 cells, where it interacts with hexokinase II, an enzyme that phosphorylates glucose during glycolysis switching bioenergetics from aerobic glycolysis to OXPHOS which is related to an increased tumor resistance to radiation treatment (107), this interaction was also observed in another study in neonatal rat ventricular myocytes under glucose starvation (108).