Stage II colorectal cancer. Poor prognosis is associated with low expression of the genes PIGR, CXCL13, MMP3, TUBA1B, CXCL10, and high expression of SESN1, AZGP1, KLK6, EPHA7, SEMA3A, DSC3 ENPP3, BNIP3 and ENPP3. The gene discussed is CXCL10; the disease is colorectal cancer.