Additionally, there was a good correlation between OEA levels and NAPE-PLD/FAAH expression ratios (Figure 1) indicating that although this NAE may be involved in the pathogenesis of endometrial cancer (1), its production is regulated by alterations in the activities of NAPE-PLD and FAAH at the tissue level rather than at the lymphocytic level. This evidence concerns the gene NAPEPLD and endometrial cancer.