GPLD1 and endometrial cancer: Since AEA, OEA and PEA levels are higher in endometrial cancer tissues (1), we adduced that either a reduction in FAAH expression, or an increase in NAPE-PLD expression, or both, occurring simultaneously, might be responsible for the observed higher tissue levels of these endocannabinoids (collectively referred to as N-acylethanolamines or NAEs).