Using OSbrca, we showed that PGK1 gene was indeed a poor survival biomarker in breast cancer cohorts (top 6 samples): TCGA [OS, HR (95% CI) = 2.42 (1.74–3.36), P < 0.0001], GSE20685 [OS, HR (95% CI) = 2.11 (1.35–3.39), P = 0.001], GSE17705 [RFS, HR (95% CI) = 2.44 (1.51–3.95), P < 0.001], GSE2034 [MFS, HR (95% CI) = 1.60 (1.06–2.41), P = 0.0257], GSE269721 [MFS, HR (95% CI) = 1.83 (1.06–3.15), P = 0.0291], and GSE31448 [DFS, HR (95% CI) = 1.67 (1.03–2.69), P = 0.0364] (Figure 1). Here, PGK1 is linked to breast cancer.