After adjustment for the potential confounders, including age and menopausal status, the association of CCL5 rs2107538-C/T genotype (P = 0.034), CCL5 rs2107538-T/T genotype (P = 0.011), CCND1 rs614367-T/T genotype (P = 0.021) and HS6ST3 rs1924587-C/C genotype (P = 0.019) with BC risk remained significant. The gene discussed is CCL5; the disease is breast cancer.