IL1R2 and breast cancer: Tissue microarray (TMA) analysis was then applied to determine IL1R2 expression in different BC molecular subtypes (Luminal A, Luminal B, Her2+, and Basal like), as shown in Figure 1G, IL1R2 protein level was significantly upregulated in all four subtypes of BC tissues compared to that in normal tissue, while there was no significant difference across the molecular subtypes.