ADK and breast cancer: To evaluate the possible mechanisms and genes that contribute to cellular phenotypic changes of ADK modified MBA-MB-231 breast cancer cells, we explored the gene expression profiles using an RT2 profiler PCR array and compared 84 genes between cultured MDA-MB-231 cells with or without ADK-L knockdown (i.e., MDA-ADK-LD vs MDA-WT) (Figure 5).