CD8A and neoplasm: Consistent with the increased DC, NK and T cell functions, NanostringTM analysis revealed large and significant increases in non-injected tumor infiltrating immune cell marker genes (cell type scores) for DCs, activated NK cells, T cells, CD8+ T cells, and cytotoxic cells resulting from combination therapy compared to the monotherapies, while no change occurred in B cell signature scores (Figure 4F & Supplementary Figure 4B).