Photomicrographs reepresentative for four independent experiments illustrate the average numbers of apoptotic cells (Casp3+) in (A) liver, (B) kidney and (C) lung in at least six high power fields (HPF) as quantitatively assessed in paraffin sections of respective ex vivo biopsies applying in situ immunohistochemistry at day 6 post-infection (100× magnification, scale bar 100 μm). The gene discussed is CASP3; the disease is infection.