We also estimated the risk of GDM associated with every 1-log μg/L increment in RBP4 levels, and the OR (95% CI) in model 3 was 3.12 (1.08~9.04) for RBP4 in the first trimester and 3.38 (1.03~11.08) for RBP4 in the second trimester. This evidence concerns the gene RBP4 and gestational diabetes.