TRIM27 and hepatocellular carcinoma: To verify the putative targets of miR-30b-3p, we performed the online bioinformatics software TargetScan Human 7.2 and dual-luciferase reporter assay and demonstrated that miR-30b-3p could directly target TRIM27, which has been further verified to be upregulated in 50 HCC tissues compared with that in their adjacent noncancerous tissues and negatively correlated with the levels of miR-30b-3p, suggesting that miR-30b-3p could inhibit HCC cell proliferation, migration, and invasion by downregulating TRIM27.