FGFR3 and neoplasm: The mutational state of TERTp and FGFR3 genes in bladder cancer is considered a promising predictor of recurrence of NMIBC, demonstrated by the association between FGFR3 mutation in primary tumor and later in recurrence events (Hernandez et al., 2006; Burger et al., 2008; Kompier et al., 2009; Miyake et al., 2010; Zuiverloon et al., 2010; van Rhijn et al., 2012).