DNAJC5 and malaria: Moreover, HBsAg VLP already demonstrated to be safe in humans as carrier for heterologous (malaria) antigens: the most clinically advanced anti-malaria vaccine RTS,S/AS01 MosquirixTM (a pre-erythrocytic vaccine) is based on a recombinant HBsAg genetically fused to part of the P. falciparum circumsporozoite protein (CSP) co-expressed with unfused HBsAg, to assemble into a mosaic VLP displaying CSP.