CD3E and neoplasm: In marked contrast, in the Py230-based primary tumors, F4/80+ macrophages remained the predominant immune cell type (34%) at 6 w p.i., although closely followed in numbers by Ly6G+ neutrophils (16%) and CD3ε+ T-cells (24%), together approximating 75% of the primary tumor immunophenotype (Figure 5H).