Searching for new biomarkers that would allow a better identification of the population at risk, circulating immune complexes (CIC) of IgA bound to B2GP1 (B2A-CIC) were described in the blood of patients with APS symptomatology (22) and its presence was associated with the occurrence of acute thrombotic events (23). This evidence concerns the gene CD79A and autoimmune polyendocrinopathy.