Even if the virus does not reach the fetus, the level of the maternal inflammatory response and the levels of inflammatory cytokines, such as interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor (TNF)-α are very high, which can affect the development of the fetal brain and circulatory system, and may increase the risk of schizophrenia, autism, and mental disorders (38). The gene discussed is TNF; the disease is mental disorder.