TNF and psychiatric disorder: Even if the virus does not reach the fetus, the level of the maternal inflammatory response and the levels of inflammatory cytokines, such as interleukin (IL)-1, IL-6, IL-8, and tumor necrosis factor (TNF)-α are very high, which can affect the development of the fetal brain and circulatory system, and may increase the risk of schizophrenia, autism, and mental disorders (38).