Experiments performed in a p53-inducible metastatic model of ovarian cancer revealed an MHCIIloCD40loPD-L1hi subset of DCs which suppressed CD8+ T cell proliferation and failed to induce IFN-γ and Granzyme B production, an effect attributed to TGFβ and prostaglandin E2 (PGE2). Here, CD8A is linked to ovarian carcinoma.