PEMs + tumor-derived CCL2: proinflammatory cytokines TNFα ↑, IL18↑, IL-12 not detectable (RT-PCR), rCCL2 treatment of PEMs: IL12↑ (ELISA), TAM from tumors +/– CCL2: IL12 (=), TNFα (=), IL18 (=) (ELISA). Here, IL18 is linked to neoplasm.