SIRS vs. normal sera: M2 marker CCL17↑ (ELISA), M2 marker mannose receptor↑ (RT-PCR)  PEMs of mice + SIRS sera: CCL17↑, with anti-CCL2-Ab: CCL17↓, PEMs of normal mice + rCCL2: CCL17↑ (ELISA). The gene discussed is CCL2; the disease is systemic inflammatory response syndrome.