Cyclophilin A has been implicated in the life cycles of several viruses and plays a critical role in the successful infectivity and replication of these viruses, including some tumor viruses, such as HBV and HCV (Bose et al., 2003; Naoumov, 2014; Jyothi et al., 2015; Phillips et al., 2015). This evidence concerns the gene PPIA and neoplasm.