This TMT-quantitative proteomics identified multiple cathepsin family members, including cathepsin L1, cathepsin B, cathepsin G, cathepsin D, cathepsin Z, cathepsin S, cathepsin F, cathepsin W, and pro-cathepsin H, in human NFPA tissues (Supplemental Table 1). This evidence concerns the gene CTSB and non-functioning pituitary adenoma.