CXCL12 and neoplasm: Another study shows that CXCR4 mRNA is expressed in 92% of growth hormone secretory pituitary adenomas (GHoma) and 81% NFPAs, whereas SDF1 is found in 63% of GHomas and 78% of NFPAs; and CXCR4 and SDF1 are the strong homogenous markers in all tumor cells of GHomas and NFPAs (18).