AdipoRON treatment also mimicked adiponectin's established anti-diabetic effects (163) and ability to enhance cellular capacity for mitigating oxidative-stress (162, 164), enhancing lipid/glucose oxidation in mitochondria (162, 164), anti-inflammatory responses (162, 164–167), life-prolonging effect (162, 163), anti-cancer effects (168, 169), pro-cell survival and anti-apoptotic effect (170, 171), neuronal- (172, 173), reno- (174, 175), and cardio-/vascular-protective effects (165, 176–179). The gene discussed is ADIPOQ; the disease is cancer.