PLXND1 and acute myeloblastic leukemia with maturation: Thus, allergic inflammation may facilitate anti-plexin D1 antibodies through the molecular mimicry of carbohydrates such as plexin D1 and environmental allergens, including Dpt. IgG2 is a low inducer of complement activation and antibody-dependent cell-mediated cytotoxicity compared with IgG1 (57, 59), which might explain the observation that anti-plexin D1 antibody-positive NeP patients, especially AM patients, experience only minor disabilities other than NeP (6).