AARS2 and leukoencephalopathy with vanishing white matter: Adrenoleukodystrophy (ALD), adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP), vanishing white matter disease (VWM), and cerebral autosomal dominant arteriopathy with subcortical infarcts and leukodystrophy (CADASIL) were all preemptively excluded to determine AARS2 complex heterozygous mutations.