Inflammatory cells, including macrophages and neutrophils, will be incorporated into a model of post-MI wound healing as the primary source and modulators of inflammatory cytokines and TGFβ input, as has been demonstrated previously in simulations of skeletal muscle and lung fibrosis (Martin et al., 2016; Warsinske et al., 2016; Virgilio et al., 2018). This evidence concerns the gene TGFB1 and pulmonary fibrosis.