SMN1 and chronic kidney disease: Within the CKD animals, the BCAA group showed, compared with the 8 + 10 group, a significant increase in the expression of all three tested collagens [1A1 (p < 0.005), 1A2 (p < 0.05), and 3A1 (p < 0.05)] as well as α SMA (p < 0.05) compared with the 8 + 10 group.