In PD, induced in mouse models by 6-hydroxydopamine injection into the nigrostriatal pathway (Chung et al., 2008) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (Holmer et al., 2005) EAAT2 expression is reduced. This evidence concerns the gene SLC1A2 and Parkinson disease.