An increasing number of novel lncRNAs including GAS5, SOX2OT, HOTTIP, OIP5-AS, LINC00473, etc. are potential biomarkers for NSCLC diagnosis and prognosis and should be validated in large NSCLC samples (Chen et al., 2016c; Esfandi et al., 2019; Kamel et al., 2019; Navarro et al., 2019). This evidence concerns the gene HOTTIP and non-small cell lung carcinoma.