Knockdown of NNT-AS1 results in cell cycle arrest, inhibits cell proliferation, and promotes cell apoptosis via downregulation of MAPK/Slug signaling pathway, which suggests MAPK/Slug pathway mediates NNT-AS1 induced DDP resistance in NSCLC (Cai et al., 2018). This evidence concerns the gene SNAI2 and non-small cell lung carcinoma.