In male Sprague-Dawley rats, infusion of NEfor seven days reduce the expression of myosin heavy chain 11, myosin light chain 3 and troponin I. In patients with heart failure, the expression of a number of sarcomeric genes decreases, while their expression is restored in those having left ventricular assisted device (Rodrigue-Way et al., 2005). Here, MYH11 is linked to heart failure.