Consequently, we hypothesized that the anti-stroke effects of salidroside on MCAO-induced cerebral ischemia/reperfusion in rats may be involved in monoamine metabolism-induced modulation of the TH-positive cells in the CPu and the SNpc, which may be related to the function of the dopaminergic system in the brain (Figure 8). This evidence concerns the gene TH and Cerebral ischemia.