The results of microarray analysis and bioinformatics prediction tools revealed that the downregulated miR-138-5p in HBMEC/PHT cells could directly bind to the KCNQ1OT1 and NF-κB p65 transcripts, and this effect was confirmed by luciferase assays. This evidence concerns the gene KCNQ1OT1 and pulmonary hypertension, primary, 1.