Transcription factor that is a key regulator of adipogenesis and B cell development. KLF3 serves as a key regulator of neuronal development, and dysregulation of regulators in the KLF famiuly has been linked to has been linked to various neurological disorders. KLFs may play a key role in brain vasoprotection and neuroprotection in response to ischemic or hypoxic stimuli. The gene discussed is KLF3; the disease is nervous system disorder.