Formerly, studies have shown that ZFPM2 was involved in tumor pathogenesis in several cancers (Hoene et al., 2009; Laitinen et al., 2000), and have suggested the tumor‐suppressive effect of ZFPM2 (Hyun et al., 2009; Manuylov, Smagulova, and Tevosian, 2007). Therefore, we focused on the exploration of ZFPM2. This evidence concerns the gene ZFPM2 and cancer.