Testing the reason for prolonged survival of MMP-9-deficient mice with B-ALL, we did not observe any significant differences in the homing efficiency of GFP+ (BCR-ABL1+) BP-1+ LIC, which represent the LIC in this model (DSK, unpublished data), to a wild type or MMP-9-deficient BMM (Fig. S3A). The gene discussed is MMP9; the disease is precursor B-cell acute lymphoblastic leukemia.