For both patient A6580 (Fig. 2c, Supplementary Table S4) and patient A6912 (Fig. 2d, Supplementary Table S4), xenografted tumours at each site were highly correlated with the patient sample, including conservation of MYCN and ALK amplification, chromosome 1p loss and chromosome 17q gain in each. The gene discussed is MYCN; the disease is neoplasm.