In contrast, a PDX model established for patient A7012 from cytogenetic residual cells (CCI-NB03-DPC) showed features of poorly differentiated neuroblastoma consistent with the original tumour, NB84 and PHOX2B positivity (Fig. 4c), and strongly correlated with the patient material by SNP array (Supplementary Fig. S1, r = 0.71). This evidence concerns the gene PHOX2B and neoplasm.