NEFL and amyotrophic lateral sclerosis: Receiver operating characteristic (ROC) analysis was used to compare the performance of plasma Nf-L and matched DBS elutes Nf-L to disciminate ALS individuals from controls (plasma: p < 0.0001, AUC: 0,9433; DBS elute: p < 0.0001, AUC: 1; Fig. 3C.2).