SELENBP1 and neoplasm: Next, we analyzed the relationship between SELENBP1 expression and clinicopathological features in bladder cancer by using TCGA-BLCA cohort (Table 1), and found that low expression of SELENBP1 was markedly correlated with non-papillary subtype (Papillary: 52% vs. Non-papillary: 64%; p = 0.023), and advanced tumor-node-metastasis (TNM) stage (I/II: 53% vs. III/IV: 64%; p = 0.029), and distant metastasis with marginal statistical significance (p = 0.057), but not with age, gender, lymphovascular invasion (LVI) or other clinicopathological features.