Log-rank test of the OS curves in TCGA-BLCA cohort indicated that bladder cancer patients with low SELENBP1 expression were remarkably related to worse prognosis than those with high SELENBP1 expression (Fig. 1d), implying that SELENBP1 might serve as a tumor suppressor in bladder cancer. The gene discussed is SELENBP1; the disease is urinary bladder cancer.