To verify this notion, we established stable transfectants expressing HA-tagged SELENBP1 protein in human colon cancer HCT116 wild-type cells (HCT116 WT) and p21 knockout cells (HCT116 p21−/−), in both of which endogenous protein levels of SELENBP1 were undetectable [30]. Here, CDKN1A is linked to colonic neoplasm.