PTPRC and graft versus host disease: As shown in Figure 4C (F→M model) and Supplemental Figure 4C (B6→129 model), acute GVHD led to an early trend (day 2 in the F→M model and day 7 in the B6→129 model) for an increase in the frequency of the CD45–VCAM1hiICAM1hi population but, in both models, this early increase was not sustained compared with BMT mice without acute GVHD (Figure 4C).