Liver explants of CLP mice that were pretreated with pemafibrate displayed increased OCR upon PA addition compared with vehicle‐treated CLP mice, indicating that increased PPARα levels improved the flux through the hepatic β‐oxidation pathway, which may contribute to the decreased levels of systemic FFAs after sepsis (Fig 5I, all timepoints in Appendix Fig S4). The gene discussed is PPARA; the disease is Sepsis.