CHI3L1 and Hepatic fibrosis: Chitinase 3‐like 1 (CHI3L1) is a member of the chitinase family, which can combine with chitin but lacks chitinolytic activity.10 CHI3L1 makes a difference in the process of inflammation and tissue remodeling11 Recently, CHI3L1 mRNA expression was characterized by tissue specificity, which level was highest in the liver.12 Johansen et al13 reported that the expression level of CHI3L1 in serum could evaluate the degree of liver fibrosis.