In a variety of cancer types overexpression of miR-9 is observed, which inhibits MHC I (Major Histocompatibility Complex) protein expression on tumor cells; or miR-222 and miR-339, thus decreasing gene expression encoding ICAM-1 adhesive protein, leading to the dysfunctional recognition of tumor cells by the immune system [75–77]. The gene discussed is PROS1; the disease is neoplasm.