Wenxin granules may regulate the inflammation-related TGFβ-p38/JNK MAPK signaling pathway and attenuate the collagen deposition of ECM, so as to inhibit the damage of myocardial tissue structure caused by ischemia injury after MI and improve cardiac function by changing the structural properties of myocardium and scar. Here, TGFB1 is linked to ischemia.