SPTLC2 and peripheral neuropathy: Lethal in SPTLC1(-/-) or SPTLC2(-/-) mice [23];↓SPT activity, ↓Ceramide in SPTLC1(+/-) or SPTLC2(+/-) mice [23];Peripheral neuropathy in SPTLC1 p.C133W mutant mice [27];Neural degeneration and ↑C20-LCB in Stellar mice [17]