Li et al., however demonstrated that KCNQ1OT1 downregulation attenuated myocardial ischemia/reperfusion injury from acute myocardial infarction, possibly by regulating adiponectin receptor 1 (AdipoR1)-p38 /NF-κB signaling cascade [28]. This evidence concerns the gene KCNQ1OT1 and acute myocardial infarction.