In addition, CDH1 showed negative association with stromal score (r2=-0.191), while stromal score positively correlated CDH2 (r2=0.337), SNAI1 (r2=0.199), SNAI2 (r2=0.201) and TWIST1 (r2=0.305) mRNA expression in ccRCC patients from TCGA cohort. This evidence concerns the gene SNAI1 and nonpapillary renal cell carcinoma.