With regard to antipsychotic treatment, there is animal evidence that D2 dopamine receptor signalling contributes to regulating cardiac function.37 There is also evidence that antipsychotics impair cardioprotection by blocking D2 receptors in a rat model of hypoxia-induced cardiomyocyte injury,37 thus potentially contributing to cardiac fibrosis. The gene discussed is DRD2; the disease is fibrosis.