These observations are in accordance with previous studies of intradermal A-07 tumors, having revealed a close link between angiogenic activity and tumor growth rate [29], reduced angiogenesis after treatment with an anti-VEGF-A antibody [34], and reduced growth rate and vessel density after treatment with sunitinib, a tyrosine kinase inhibitor targeting the VEGF receptors (VEGFR) [35]. This evidence concerns the gene VEGFA and neoplasm.